# Indications, Management, and Short- and Medium-Term Outcomes of Patients with Chronic Coronary Occlusion Treated with Percutaneous Revascularization—A Single-Center Study

**Authors:** Lucia Barbieri, Gabriele Tumminello, Lorenzo Mafrici, Guido Pasero, Luca Mircoli, Federico Colombo, Cecilia Gobbi, Alessandra S. Rizzuto, Stefano Carugo

PMC · DOI: 10.3390/jcdd12020075 · Journal of Cardiovascular Development and Disease · 2025-02-16

## TL;DR

This study examines the outcomes of patients with chronic coronary occlusion treated with a specific procedure, showing high success and low complications.

## Contribution

The study provides real-life evidence on the effectiveness and safety of percutaneous revascularization for chronic total occlusion.

## Key findings

- PCI for CTO has a high success rate in real-life clinical settings.
- The procedure is associated with a low incidence of major complications.
- Patients showed improved outcomes with minimal residual cardiac symptoms.

## Abstract

The diagnosis of chronic total occlusion (CTO), characterized by the complete obstruction of a coronary artery for at least three months, remains challenging and can be entirely asymptomatic. Since the indications for performing a recanalization procedure for CTO do not originate from randomized controlled trials, this study aimed to assess the indications, management, and procedural outcomes of patients undergoing percutaneous revascularization (PCI) for a CTO, ensuring that the population was as uniform as possible regarding technologies and methodological approaches. Forty-one consecutive patients who underwent PCI for CTO recanalization were enrolled from January 2021 to 2024. Additional outcomes included mortality, major adverse cardiovascular events, and the presence of residual cardiac symptoms, with a median follow-up of 449 days and an interquartile range of 230–643 days. Our real-life study confirmed that PCI for CTO has a high success rate and a low incidence of major complications.

## Full-text entities

- **Diseases:** CTO (MESH:D001157), coronary artery (MESH:D003324), Chronic Coronary Occlusion (MESH:D054059), cardiac symptoms (MESH:D006331)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC11856296/full.md

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Source: https://tomesphere.com/paper/PMC11856296