# Healthy Behavior for Preventing Cognitive Disability in Older Persons

**Authors:** Fulvio Lauretani, Antonio Marcato, Crescenzo Testa

PMC · DOI: 10.3390/ijerph22020262 · International Journal of Environmental Research and Public Health · 2025-02-12

## TL;DR

This paper discusses how balancing physical activity and avoiding excessive sitting can prevent cognitive decline and disability in older adults.

## Contribution

The paper emphasizes the importance of integrating physical and cognitive health strategies in geriatric care to prevent disability.

## Key findings

- Excessive sitting nullifies the benefits of physical activity in preventing cognitive disability.
- Balancing physical activity and sedentary behavior is crucial for reducing cardiovascular and cognitive risks.
- Preclinical stages like MCR Syndrome highlight the need for integrated physical and cognitive health interventions.

## Abstract

Sufficient levels of physical activity are fundamental for preventing cardiovascular disease, dementia, and ultimately disability in older persons, yet this protective factor is nullified when excessive hours are spent in continuous sitting. Balancing physical activity and sedentary behavior is crucial for influencing metabolic parameters and vascular patterns, both central and peripheral, thereby reducing the risk of cardiovascular diseases, vascular dementia, and cognitive impairment. The primary goal of geriatric medicine is to improve quality of life and prevent disability by promptly identifying frail older individuals, thus mitigating both cognitive and motor impairments. Achieving this objective requires not only the optimization of pharmacological treatments but also the active promotion of a healthy lifestyle. In this context, investigating preclinical stages of disability, such as Motoric Cognitive Risk (MCR) Syndrome, which integrates physical and cognitive components of decline, becomes essential. However, despite robust evidence supporting these interventions, greater efforts are needed from the geriatric medical community to bridge the gap between scientific recommendations and everyday clinical practice. Integrating these guidelines into routine care is pivotal for delivering personalized interventions that address both physical inactivity and prolonged sedentary behavior. More research should aim to strengthen this balance, providing clearer, actionable strategies for clinicians to implement, thereby fostering the formation of evidence-based public health guidelines on physical activity specifically tailored for older persons.

## Linked entities

- **Diseases:** dementia (MONDO:0001627), vascular dementia (MONDO:0004648), cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** cardiovascular disease (MESH:D002318), Cognitive Disability (MESH:D003072), vascular dementia (MESH:D015140), physical inactivity (MESH:C564765), dementia (MESH:D003704)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11855899/full.md

## References

29 references — full list in the complete paper: https://tomesphere.com/paper/PMC11855899/full.md

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Source: https://tomesphere.com/paper/PMC11855899