# Cystinuria-Related Urinary Stone as the Cause of Repeated Urinary Tract Infections (UTIs) in a Child

**Authors:** Anastasios Panagiotis Chantzaras, Spyridon Karageorgos, Anna Papakonstantinou, Christos Kyriopoulos, Panagiotis Mitsos

PMC · DOI: 10.7759/cureus.78003 · 2025-01-26

## TL;DR

A four-year-old child with repeated urinary tract infections was found to have a bladder stone caused by cystinuria, highlighting the need for thorough evaluation in pediatric UTI cases.

## Contribution

This case report highlights cystinuria-related urolithiasis as a rare but important cause of recurrent UTIs in children.

## Key findings

- A 4.4 cm bladder stone was diagnosed in a child with recurrent UTIs.
- The UTIs were caused by Enterococcus faecalis and linked to cystinuria-related urolithiasis.
- The case underscores the importance of clinical and radiographical evaluation in recurrent pediatric UTIs.

## Abstract

Urinary tract infections (UTIs) are one of the most common bacterial infections in children and are associated with both acute and long-term complications. Most UTIs typically resolve after antibiotic treatment. However, UTIs may be the initial clinical manifestation of a potential congenital anomaly of the kidneys and the urinary tract (CAKUT) or may indicate the presence of a renal stone. Especially in pediatric patients presenting with early and recurrent episodes of UTIs, a thorough clinical and radiographical evaluation is warranted.

Our manuscript presents a case of a four-year-old male patient diagnosed with a 4.4 cm-diameter stone in his bladder. The patient was investigated for recurrent Enterococcus faecalis lower UTIs and was finally diagnosed with cystinuria-related urolithiasis.

## Linked entities

- **Diseases:** cystinuria (MONDO:0009067), urolithiasis (MONDO:0024647)

## Full-text entities

- **Diseases:** urolithiasis (MESH:D052878), bacterial infections (MESH:D001424), congenital anomaly of the kidneys and the (MESH:D007680), renal stone (MESH:D007669), UTIs (MESH:D014552), Cystinuria (MESH:D003555)
- **Species:** Homo sapiens (human, species) [taxon 9606], Enterococcus faecalis (species) [taxon 1351]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11855169/full.md

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Source: https://tomesphere.com/paper/PMC11855169