Multifilm Mass Transfer and Reaction Rate Kinetics in a Newly Developed In Vitro Digestion System for Carbohydrate Digestion
Yongmei Sun, Jingying Cheng, Shu Cheng, Timothy A. G. Langrish
TL;DR
A new in vitro digestion system models carbohydrate digestion dynamics and helps distinguish low and high glycemic index foods.
Contribution
A novel in vitro digestion system with comparable in vivo dynamics and the ability to estimate glycemic index (GI) values.
Findings
The in vitro model replicates in vivo dynamics with similar Reynolds numbers.
The system can differentiate low and high GI foods based on glucose measurements.
Glucose transport and glycemic responses match in vivo results for banana and carrot.
Abstract
Multifilm mass transfer theory has been used in conjunction with developing a new in vitro starch digestion model and applied to assessing starch digestion kinetics. One significance of this research is that this in vitro model has similar dynamics, such as similar Reynolds numbers for both in vivo and in vitro systems. In the in vitro intestine model, when the flow rate changes from 5.9 × 10−6 m3 s−1 to 1.0 × 10−5 m3 s−1 inside the intestine wall (inside the sausage casing), the Re number changes from 362 to 615. An oral digestion model, a stomach model, and an intestine model have been built to quantitatively understand reaction rate kinetics and two-film (or multifilm) mass transfer for carbohydrate digestion. This in vitro digestion system represents the oral mastication process to reduce the length scale of the test food, amylase inhibition in the stomach, and glucose generation…
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Taxonomy
TopicsFood composition and properties · Polysaccharides Composition and Applications · Proteins in Food Systems