# Pulmonary arteriovenous malformation causing lung sequestration and media infarction: a case report

**Authors:** Raffaella Griffo, Laura V. Klotz, Lena Brendel, Romina Rösch, Benedikt Niedermaier, Kai Schlamp, Mark Kriegsmann, Martin M. Eichhorn, Hauke Winter

PMC · DOI: 10.3389/fmed.2025.1490820 · 2025-02-11

## TL;DR

This case report describes a rare lung condition causing oxygen inefficiency and a stroke, emphasizing the need for early treatment.

## Contribution

The report highlights a complex PAVM case with stroke onset and a persistent foramen ovale, emphasizing interdisciplinary management.

## Key findings

- A PAVM case presented with stroke as the initial symptom and a persistent foramen ovale.
- Despite treatment, a fatal pulmonary complication occurred, underscoring the need for early and ongoing care.

## Abstract

Pulmonary arteriovenous malformations (PAVMs) are rare vascular malformations of the lungs. Direct communication of pulmonary arteries to pulmonary veins is the defining characteristic allowing venous blood to bypass the pulmonary capillary system and avoiding an efficient oxygenation process. The complexity of the pathology lies not only in the variety of its manifestations, but also in the choice of the most appropriate and effective treatment. We present a case of a complex PAVM associated with a persistent foramen ovale, with stroke as the onset symptom. Despite timely multidisciplinary treatment of the malformation, a potentially fatal pulmonary complication occurred, highlighting the critical importance of early, interdisciplinary management and ongoing follow-up of PAVMs, particularly in preventing life-threatening outcomes.

## Linked entities

- **Diseases:** stroke (MONDO:0005098), pulmonary arteriovenous malformation (MONDO:0009930)

## Full-text entities

- **Diseases:** infarction (MESH:D007238), stroke (MESH:D020521), vascular malformations (MESH:D054079), lung sequestration (MESH:D001998), pulmonary complication (MESH:D008171), persistent foramen ovale (MESH:D054092), PAVMs (MESH:D001165)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11850261/full.md

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Source: https://tomesphere.com/paper/PMC11850261