# Guidelines for Parkinson's disease management part II: consensus from the movement disorders scientific department of the Brazilian Academy of Neurology – non-motor symptoms

**Authors:** Débora Palma Maia, Rubens Gisbert Cury, Pedro Renato P. Brandão, Francisco E. C. Cardoso, Ana Paula Bertholo, André Carvalho Felicio, Arlete Hilbig, Bruno Lopes Santos Lobato, Eline Rozária F. Barbosa, Elizabeth Maria A. B. Quagliato, Gustavo H. C. Sousa, Jacy Bezerra Parmera, Márcia Rúbia, Marcus Vinícius Della Coletta, Maria Sheila Guimarães Rocha, Mariana Spitz, Mônica Haddad, Nina Rosa A. F. Murta, Paulo Caramelli, Raimundo N. D. Rodrigues, Ricardo Nitrini, Roberto Prado, Vitor Tumas, Ylmar Corrêa Neto, Roberta Arb Saba

PMC · DOI: 10.1055/s-0045-1802962 · Arquivos de Neuro-Psiquiatria · 2025-02-24

## TL;DR

This paper presents guidelines for managing non-motor symptoms of Parkinson's disease, tailored for the Brazilian population.

## Contribution

It provides consensus-based recommendations for non-motor symptom treatment by Brazilian movement disorder specialists.

## Key findings

- Non-motor symptoms like depression and sleep disorders were addressed with specific therapies.
- Recommendations for managing pain and dysautonomia were included in the guidelines.
- The guidelines aim to adapt global evidence to better suit the Brazilian context.

## Abstract

The treatment of Parkinson's disease (PD) is a challenge, especially because it is considered highly individualized. The Brazilian Academy of Neurology (ABN) has identified the need to disseminate knowledge about its management, adapting the best evidence to the Brazilian population. The present article aims to report the recommendations for the treatment of non-motor symptoms of PD, developed by a group of specialists in movement disorders from the ABN's scientific department. In 2021, the first part, referring to the motor symptoms of PD, was published. The main non-motor symptoms were addressed—among them neuropsychiatric symptoms, such as depression, anxiety, cognitive alteration, and psychosis—as well as the possible recommended therapies and medications used to control pain, sleep disorders, and dysautonomia.

## Linked entities

- **Diseases:** Parkinson's disease (MONDO:0005180), depression (MONDO:0002050), anxiety (MONDO:0005618), psychosis (MONDO:0005485)

## Full-text entities

- **Diseases:** dysautonomia (MESH:D054969), pain (MESH:D010146), movement disorders (MESH:D009069), neuropsychiatric symptoms (MESH:D001523), non-motor symptoms (MESH:D020879), psychosis (MESH:D011618), cognitive alteration (MESH:D003072), depression (MESH:D003866), PD (MESH:D010300), sleep disorders (MESH:D012893), anxiety (MESH:D001007)

## Full text

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## References

167 references — full list in the complete paper: https://tomesphere.com/paper/PMC11850083/full.md

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Source: https://tomesphere.com/paper/PMC11850083