# First person – Sophie Badger

## TL;DR

This paper introduces a new mouse model for studying amyotrophic lateral sclerosis and features an interview with the first author, Sophie Badger.

## Contribution

The paper presents a novel bacterial artificial chromosome mouse model for ALS that exhibits 'space cadet syndrome'.

## Key findings

- The mouse model manifests 'space cadet syndrome' on two FVB backgrounds.
- The model is being used to investigate gene therapy for C9orf72-associated ALS/FTD.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Sophie Badger is first author on ‘
A bacterial artificial chromosome mouse model of amyotrophic lateral sclerosis manifests ‘space cadet syndrome’ on two FVB backgrounds’, published in DMM. Sophie conducted the research described in this article while a PhD student in James Alix's lab at the University of Sheffield, Sheffield, UK. She is now a postdoctoral research associate in the lab of Guillaume Hautbergue at the University of Sheffield, investigating a potential gene therapy for C9orf72-associated amyotrophic lateral sclerosis (ALS)/frontotemporal dementia (FTD).