# Case Report and Literature Review of Conjunctival Melanoma in the Black Population

**Authors:** Oscar Chen, Fae Kayarian, Elaine Kelly, Richard J. Grostern, Anjali Tannan

PMC · DOI: 10.1155/crop/5578922 · Case Reports in Ophthalmological Medicine · 2025-02-14

## TL;DR

This paper reports a rare case of conjunctival melanoma in a Black patient and reviews all documented cases in the Black population.

## Contribution

The paper adds a new case report and compiles 46 previously documented cases of conjunctival melanoma in Black individuals.

## Key findings

- A 46-year-old Black male was diagnosed with extensive conjunctival melanoma in situ and required multiple treatments.
- A literature review identified only 46 prior cases of conjunctival melanoma in the Black population.
- Conjunctival melanoma is extremely rare in Black individuals, with only 47 total documented cases.

## Abstract

Purpose: The purpose of this study is to report a rare case of conjunctival melanoma (CM) in a black male patient and provide a comprehensive literature review of all documented cases of CM in the black population.

Methods: A case report highlighting a black patient with newly diagnosed CM was described. A comprehensive literature review was conducted to determine the prevalence of CM in the black population.

Results: Extensive CM in situ in a 46-year-old black male patient was treated with excision and cryotherapy. The patient subsequently required repeat cryotherapy and topical Mitomycin C therapy due to a recurrence of pigmentation. A literature review identified 46 cases of CM in the black population.

Conclusions: CM has rarely been observed in the black population. With this current case report, there are only 47 black patients found in the literature with this ocular surface tumor. Further detailed documentation on the presentation, location, and outcomes of CM in this population is imperative to better screen and treat this demographic.

## Linked entities

- **Chemicals:** Mitomycin C (PubChem CID 5746)
- **Diseases:** conjunctival melanoma (MONDO:0002096)

## Full-text entities

- **Diseases:** pigmentation (MESH:D010859), CM (MESH:D008545), ocular surface tumor (MESH:D009369)
- **Chemicals:** Mitomycin C (MESH:D016685)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11845260/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11845260/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC11845260/full.md

---
Source: https://tomesphere.com/paper/PMC11845260