# Pulmonary Metastases of Mixed Adenoid Cystic and Squamous Cell Carcinoma of the Uterine Cervix: A Report of a Rare Case

**Authors:** Meriem Rhazari, Afaf Thouil, Imane Kamaoui, Hatim Kouismi

PMC · DOI: 10.7759/cureus.77822 · Cureus · 2025-01-22

## TL;DR

A rare case of cervical cancer with mixed adenoid cystic and squamous cell components leading to lung metastases is reported.

## Contribution

This paper reports a rare case of mixed adenoid cystic and squamous cell carcinoma of the uterine cervix with pulmonary metastasis.

## Key findings

- The patient had a mixed carcinoma with both adenoid cystic and squamous cell components in the cervix.
- Pulmonary metastases were confirmed through biopsy and attributed to the cervical tumor.
- The case highlights the complexity of diagnosing and managing mixed carcinomas of the cervix.

## Abstract

Cystic adenoid carcinoma (CAK) is a rare malignant tumor primarily affecting the salivary glands, but it can also involve other sites, including the uterine cervix. This tumor is associated with a high potential for local recurrence and pulmonary metastasis. We present the case of a 73-year-old diabetic woman with a history of cervical adenocarcinoma treated with radiochemotherapy and total hysterectomy. She was hospitalized for acute dyspnea, and imaging revealed pulmonary lesions, which were confirmed by biopsy as pulmonary metastases of CAK. A review of the hysterectomy specimen revealed a mixed carcinoma with both adenoid cystic and squamous cell components. The patient was started on palliative chemotherapy. The diagnosis and management of mixed carcinomas of the uterine cervix, including CAK, remain complex and require a multimodal approach.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), cervical adenocarcinoma (MONDO:0005153), adenoid cystic carcinoma (MONDO:0004971)

## Full-text entities

- **Diseases:** Pulmonary Metastases (MESH:D009362), cervical adenocarcinoma (MESH:D000230), Cystic adenoid carcinoma (MESH:D003528), pulmonary lesions (MESH:D008171), carcinomas of the uterine cervix (MESH:D002583), dyspnea (MESH:D004417), Adenoid Cystic and Squamous Cell Carcinoma of the (MESH:D002294), diabetic (MESH:D003920), carcinoma (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11843803/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11843803/full.md

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Source: https://tomesphere.com/paper/PMC11843803