# Anxiety Symptoms in Hypothyroidism: A Case for Causation or Co-Occurrence?

**Authors:** Eleftheria Dampa

PMC · DOI: 10.7759/cureus.77814 · Cureus · 2025-01-22

## TL;DR

A case report shows how hypothyroidism symptoms can be mistaken for anxiety, stressing the need for thorough medical evaluations.

## Contribution

Highlights the importance of endocrine evaluation in anxiety-like symptoms to avoid misdiagnosis.

## Key findings

- A 32-year-old female was misdiagnosed with anxiety for 10 months due to undiagnosed hypothyroidism.
- Thorough evaluation revealed hypothyroidism as the root cause of anxiety-like symptoms.
- The case underscores the need for thyroid testing in patients presenting with anxiety symptoms.

## Abstract

Hypothyroidism, also known as an underactive thyroid, is an endocrine condition in which the thyroid gland does not produce enough thyroid hormones to meet the body’s needs. Hypothyroidism can develop slowly over time and cause a variety of symptoms, including fatigue, muscle weakness and stiffness, cold intolerance, brain fog, anxiety, limb numbness or tingling sensation, and palpitations. The following case describes a 32-year-old female who presented with anxiety-like symptoms closely resembling the classic symptomatology of hypothyroidism. These symptoms led to a 10-month misdiagnosis of generalized anxiety disorder. The patient had never been tested for hypothyroidism, nor had she undergone a thyroid panel. Following additional assessments, the patient was diagnosed with hypothyroidism, which emphasizes the necessity of conducting a comprehensive evaluation of the endocrine system and potential root causes in individuals exhibiting anxiety-like symptoms. This case report highlights the importance of conducting thorough medical and endocrine evaluations in patients with anxiety-like symptoms to prevent misdiagnosis, avoid unnecessary treatments, and ensure proper care.

## Linked entities

- **Diseases:** hypothyroidism (MONDO:0005420), generalized anxiety disorder (MONDO:0001942)

## Full-text entities

- **Diseases:** limb numbness or tingling sensation (MESH:D006987), brain fog (MESH:D005222), fatigue (MESH:D005221), Anxiety Symptoms (MESH:D001008), generalized anxiety disorder (MESH:C000726808), muscle weakness and stiffness (MESH:D018908), Hypothyroidism (MESH:D007037), anxiety (MESH:D001007), palpitations (MESH:D006331), cold intolerance (MESH:D000067390), underactive thyroid (MESH:D000077295)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11843586/full.md

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Source: https://tomesphere.com/paper/PMC11843586