# Achieving a Good Response in Myxofibrosarcoma With Uncontrollable Bleeding Using an Enzyme-Targeting Radiosensitization Treatment: A Case Report

## TL;DR

A 78-year-old man with a large, bleeding myxofibrosarcoma tumor on his forearm was successfully treated with a non-surgical radiation therapy called KORTUC.

## Contribution

This case report demonstrates the potential effectiveness of KORTUC in treating unresectable myxofibrosarcoma.

## Key findings

- The patient showed a good response to KORTUC I and II treatments over seven years.
- KORTUC was effective in managing tumor recurrence and uncontrollable bleeding without surgery.
- This case highlights the need for further research on KORTUC for sarcomas unsuitable for surgical intervention.

## Abstract

Myxofibrosarcoma is one of the most prevalent histological types of primary malignant soft tissue tumors of the extremity. Radiation therapy is frequently employed as a post-operative treatment. In this case report, we present a 78-year-old male with a large tumor on his forearm. He refused surgical treatment. Over a period of seven years, recurrence and bleeding were repeatedly observed. Kochi oxydol radiation therapy for unresectable carcinomas (KORTUC) is a treatment modality that uses a hydrogen peroxide solution that adheres to the tumor surface (KORUTC I), while the solution is also injected into the tumor (KORTUC II). We treated the tumor with KORTUC I and II. A good response was observed. This case report highlights the effectiveness of KORTUC I and II. Reports on KORTUC for sarcomas are limited, underscoring the necessity for future examination of cases not indicated for surgical intervention.