# Integrated treatment of depression and moderate to severe alcohol use disorder in women shows promise in routine alcohol use disorder care – a pilot study

**Authors:** Anna Persson, Daniel Wallhed Finn, Alice Broberg, Amanda Westerberg, Åsa Magnusson, Olof Molander

PMC · DOI: 10.3389/fpsyt.2025.1473988 · Frontiers in Psychiatry · 2025-02-06

## TL;DR

A pilot study shows that treating depression and alcohol use disorder together in women is feasible and promising, though more research is needed.

## Contribution

This study explores the feasibility and preliminary effects of an integrated treatment for co-occurring depression and alcohol use disorder in women.

## Key findings

- Feasibility, credibility, and patient satisfaction with the integrated treatment were high.
- Depression symptoms and alcohol consumption decreased from baseline to follow-up.
- Increased adverse emotional experiences were reported as potential negative effects.

## Abstract

Major depression and alcohol use disorder affect millions of individuals worldwide and cause significant disability. They often occur together, and their co-occurrence is associated with more negative outcomes than each disorder on its own. Yet, there is a lack of knowledge on how to best treat co-occurring depression and alcohol use disorder. A pilot study was conducted to investigate the feasibility, credibility, patient satisfaction, preliminary effect, and potential negative effects of an integrated treatment for depression and alcohol use disorder, which has shown promising results in an earlier pilot trial.

The study was conducted at an outpatient unit in Stockholm, Sweden. Women (n=7) with current depression and alcohol use disorder were offered integrated group treatment that included evidence-based treatment for depression and alcohol use disorder. Criteria for feasibility were based on an earlier study, treatment credibility was measured using the Credibility/Expectancy Questionnaire and patient satisfaction with the Client Satisfaction Questionnaire.

Feasibility, credibility, and patient satisfaction were high. Depression symptom severity and alcohol consumption decreased from baseline to follow up. Negative effects were reported in terms of increased adverse emotional experiences.

The investigated integrated treatment for co-occurring depression and alcohol use disorder continues to show promise. Randomized clinical trials are needed to evaluate its effectiveness.

## Linked entities

- **Diseases:** depression (MONDO:0002050)

## Full-text entities

- **Diseases:** Depression (MESH:D003866), Major depression (MESH:D003865), alcohol use disorder (MESH:D000437)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

52 references — full list in the complete paper: https://tomesphere.com/paper/PMC11840566/full.md

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Source: https://tomesphere.com/paper/PMC11840566