# Retraction: FAM172A controls endoplasmic reticulum (ER) stress related to NF-κB signaling pathway in hepatocellular carcinoma

**Authors:** Wenfeng Shen, Zhiqiang Feng, Ping Wang, Jinqian Zhang

PMC · DOI: 10.1039/d5ra90015h · RSC Advances · 2025-02-19

## TL;DR

This retraction notice addresses a 2017 study on FAM172A's role in ER stress and NF-κB signaling in liver cancer.

## Contribution

The paper is a retraction of prior findings regarding FAM172A's involvement in hepatocellular carcinoma.

## Key findings

- The original study's claims about FAM172A and ER stress in liver cancer are retracted.
- This retraction highlights the need for verification of scientific results in this area.

## Abstract

Retraction of ‘FAM172A controls endoplasmic reticulum (ER) stress related to NF-κB signaling pathway in hepatocellular carcinoma’ by Wenfeng Shen et al., RSC Adv., 2017, 7, 51870–51878, https://doi.org/10.1039/C7RA09918E.

## Linked entities

- **Genes:** ARB2A (ARB2 cotranscriptional regulator A) [NCBI Gene 83989]
- **Proteins:** NFKB1 (nuclear factor kappa B subunit 1)
- **Diseases:** hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Genes:** ARB2A (ARB2 cotranscriptional regulator A) [NCBI Gene 83989] {aka C5orf21, FAM172A, Toupee}, NFKB1 (nuclear factor kappa B subunit 1) [NCBI Gene 4790] {aka CVID12, EBP-1, KBF1, NF-kB, NF-kB1, NF-kappa-B1}
- **Diseases:** hepatocellular carcinoma (MESH:D006528)

## Full text

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Source: https://tomesphere.com/paper/PMC11840532