# High-grade serous cancer of left fallopian tube with right inguinal lymph node enlargement: a case report

**Authors:** Aizhi Zhou, Weiyong Gu, Yumei Yang, Xin Chen, Wenfeng Ye, Mei Wang

PMC · DOI: 10.3389/fonc.2025.1486688 · 2025-02-06

## TL;DR

A 47-year-old woman was diagnosed with high-grade serous cancer in her left fallopian tube and underwent successful surgery and chemotherapy.

## Contribution

This case report provides a detailed clinical account of high-grade serous cancer metastasis to the inguinal lymph nodes.

## Key findings

- Histopathological analysis confirmed high-grade serous carcinoma in the left fallopian tube and ovary.
- Post-surgery, no residual disease was found, and the patient responded well to chemotherapy.
- PET-CT identified the tumor in the left adnexa with no other organ involvement.

## Abstract

A 47-year-old woman with a two-month history of right inguinal lymphadenopathy visited Shanghai Pudong New Area People’s Hospital for a biopsy. Histopathological and immunohistochemical analyses revealed a metastasis of high-grade serous carcinoma, likely of gynecological origin. A PET-CT scan identified a tumor in the left adnexa, with no other organ involvement. The patient underwent primary cytoreduction, including laparoscopy, hysterosalpingo-oophorectomy, omentectomy, and resection of the right deep inguinal lymph nodes at the Hospital of Obstetrics and Gynecology. No residual disease was found post-surgery. Pathological examination revealed high-grade serous cancer in the fimbria of the left fallopian tube and left ovary, while the right deep inguinal lymph nodes were negative. The patient received standard chemotherapy (Carboplatin and Taxol) and showed no new lesions after three cycles, as confirmed by imaging.

## Linked entities

- **Chemicals:** Carboplatin (PubChem CID 426756), Taxol (PubChem CID 36314)

## Full-text entities

- **Diseases:** serous cancer (MESH:D009369), node (MESH:D012804), inguinal lymphadenopathy (MESH:D006552), metastasis (MESH:D009362), serous cancer of left fallopian tube (MESH:D005185), serous carcinoma (MESH:D018297)
- **Chemicals:** Carboplatin (MESH:D016190), Taxol (MESH:D017239)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11839419/full.md

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Source: https://tomesphere.com/paper/PMC11839419