Treatment of primary esophageal lymphomas: A review

TL;DR

This paper reviews treatment options for primary esophageal lymphoma, a rare cancer, and suggests that combining therapies may be most effective.

Contribution

The paper provides a comprehensive review of treatment approaches and identifies gaps in current knowledge for primary esophageal lymphoma.

Findings

Combination therapies may be more effective than single treatments for primary esophageal lymphoma.

There is no clear consensus on the most effective treatment modality for this rare cancer.

Treatment should be tailored to the specific histological subtype of the lymphoma.

Abstract

Primary esophageal lymphoma is a rare malignancy that is difficult to diagnose and treat. While there have been significant advances in understanding the pathogenesis, clinical features, and treatment options, there is a lack of consensus on the most effective treatment approach. This literature review provides a comprehensive overview of the use of available treatment options for primary esophageal lymphoma, including surgery, radiotherapy, and chemotherapy. The review also highlights the current knowledge gaps that need to be addressed through further research. While no single treatment modality has emerged as a clear front-runner, a combination of these treatments may be the most effective approach in managing primary esophageal lymphoma, tailored to the histological subtypes.