# The elusive relationship between retinal anatomy and brain amyloid

**Authors:** Dilraj S Grewal, Sharon Fekrat

PMC · DOI: 10.1093/braincomms/fcaf038 · 2025-02-19

## TL;DR

This commentary discusses a study exploring how retinal structure and blood vessels relate to amyloid buildup in the brain.

## Contribution

The commentary highlights a novel approach to understanding brain amyloid through retinal imaging.

## Key findings

- Retinal microstructure may reflect brain amyloid burden.
- Microvasculature changes in the retina could indicate early signs of amyloid accumulation.

## Abstract

This scientific commentary refers to ‘Retinal microstructure and microvasculature in association with brain amyloid burden’, by Egle et al. (https://doi.org/10.1093/braincomms/fcaf013).

## Full-text entities

- **Diseases:** brain amyloid (MESH:D001927)

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Source: https://tomesphere.com/paper/PMC11837326