# A rare case of granular cell tumor of gall bladder

## TL;DR

A rare case of a granular cell tumor in the gall bladder was diagnosed through surgery and confirmed with histology and immunohistochemistry.

## Contribution

This paper reports a rare case of granular cell tumor in the gall bladder, expanding its differential diagnosis.

## Key findings

- Granular cell tumor was confirmed in the gall bladder via histopathology and immunohistochemistry.
- The tumor was successfully treated with margin-negative excision.
- CD68 and S100 positivity indicated a neural origin of the tumor.

## Abstract

Granular cell tumor is common over skin and subcutaneous and oral cavity. However, lesion is rare in biliary tract and ever more uncommon in gall bladder. These lesions are often misdiagnosed until proven by histology and immunohistochemistry where tumor is positive for CD 68, S 100 which points them toward neural origin of tumor. We report a case of 69-year-old male referred with a suspected gall bladder mass in Computed tomographic scan of abdomen. Laparotomy was done through Kocher’s incision and extended cholecystectomy was performed. Histopathology and immunohistochemical study helped in determining gall bladder lesion to be granular cell tumor. Therefore, granular cell tumor can be considered a possible differential diagnosis of all the gall bladder lesion suspected of cholecystitis and carcinoma. Margin negative excision of the tumor is a curative approach for the patient.