# Lower Limb Ischemia Caused by Aortic Atherosclerosis Localized in the Horseshoe Renal Isthmus

**Authors:** Keisuke Senda, Naoki Nagahara, Minami Inoue, Ken Nishikawa, Katsuyuki Aizawa, Takahiro Takeuchi, Yoshinori Ohtsu, Hideo Tsunemoto, Chihiro Suzuki, Satoshi Yasukochi

PMC · DOI: 10.1002/ccr3.70232 · Clinical Case Reports · 2025-02-18

## TL;DR

Aortic atherosclerosis in the horseshoe renal isthmus can cause lower limb ischemia and intermittent claudication.

## Contribution

Highlights a rare extrarenal vascular complication in patients with horseshoe kidneys.

## Key findings

- Sclerotic changes in the aorta due to renal isthmus compression may lead to lower limb ischemia.
- Vascular disease is an under-recognized complication in horseshoe kidney patients.

## Abstract

Intermittent claudication in patients with horseshoe kidneys may arise from sclerotic changes in the aorta due to compression by the renal isthmus. Vascular disease is a relatively lesser‐known extrarenal complication of horseshoe kidneys, but it warrants attention.

## Linked entities

- **Diseases:** atherosclerosis (MONDO:0005311)

## Full-text entities

- **Diseases:** Vascular disease (MESH:D014652), horseshoe kidneys (MESH:D000069337), extrarenal complication (MESH:D008107), Intermittent claudication (MESH:D007383), Aortic Atherosclerosis (MESH:D050197)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11835949/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11835949/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC11835949/full.md

---
Source: https://tomesphere.com/paper/PMC11835949