# Bilateral testicular mass in a 21-year-old male with a history of congenital adrenal hyperplasia: A case report

## TL;DR

A 21-year-old man with a history of congenital adrenal hyperplasia developed bilateral testicular masses due to non-adherence to treatment, diagnosed as testicular adrenal rest tumors.

## Contribution

This case highlights the importance of medication adherence in managing congenital adrenal hyperplasia to prevent complications like testicular adrenal rest tumors.

## Key findings

- The patient's non-adherence to glucocorticoid therapy led to the development of testicular adrenal rest tumors.
- Surgical biopsy confirmed the diagnosis of testicular adrenal rest tumor associated with adrenogenital syndrome.
- The case underscores the need for long-term management and monitoring in patients with congenital adrenal hyperplasia.

## Abstract

A 21-year-old man was referred because of bilateral testicular swelling from 8 months ago. He had a known history of congenital adrenal hyperplasia (21-hydroxylase deficiency) diagnosed in infancy, managed with glucocorticoid therapy since childhood. However, the patient had been non-adherent to medication for several years. The patient underwent surgery with an inguinal incision, and a biopsy from the mass was sent for frozen section. The frozen and permanent sections were consistent with “Testicular adrenal rest tumor (tumor of adrenogenital syndrome)