# The Cancer Tracking System (CATSystem): Study protocol of a randomized control trial to evaluate a systems level intervention for cervical cancer screening, treatment, referral and follow up in Kenya

## TL;DR

This study tests a web-based system in Kenya to improve cervical cancer screening and treatment follow-up.

## Contribution

The novel contribution is evaluating a systems-level web-based intervention (CATSystem) to improve cervical cancer care in Kenya.

## Key findings

- The study will assess if the CATSystem improves treatment retention for cervical cancer screening.
- Mixed methods will evaluate feasibility, acceptability, and cost-effectiveness of the intervention.
- Results may inform potential scale-up of the system in Sub-Saharan Africa.

## Abstract

Cervical cancer (CC) is preventable, yet remains a significant public health threat, particularly in Sub-Saharan Africa. Despite considerable awareness, screening rates for CC in Kenya are low and loss to follow-up following treatment for premalignant cervical lesions remains high. This study investigates the efficacy of the Cancer Tracking System (CATSystem), a web-based intervention, to improve CC screening and treatment retention.

A matched, cluster randomized controlled trial will be conducted in Kenyan government hospitals (n = 10) with five intervention and five standard-of-care (SOC) sites. The primary outcome is the proportion of women with a positive screen who receive appropriate treatment (onsite or referral). Secondary outcomes include CC screening uptake among all women and timeliness of treatment initiation. We will utilize mixed methods to assess intervention feasibility, acceptability, and cost-effectiveness.

The CATSystem has the potential to improve CC care in Kenya by leveraging existing technology to address known barriers in the screening and treatment cascade. This study will provide valuable evidence for potential scale-up of the intervention.