# Editorial: Nervous regeneration and functional recovery in the central and peripheral nervous systems: diagnostic methods, gene/cell therapies, and interventions

**Authors:** Dipa Natarajan, Ryo Hotta, Naho Fujiwara, Silvia Perin

PMC · DOI: 10.3389/fnmol.2025.1555390 · 2025-02-04

## Full-text entities

- **Genes:** PIEZO1 (piezo type mechanosensitive ion channel component 1 (Er blood group)) [NCBI Gene 9780] {aka DHS, ER, FAM38A, LMPH3, LMPHM6, Mib}, CDK9 (cyclin dependent kinase 9) [NCBI Gene 1025] {aka C-2k, CDC2L4, CTK1, PITALRE, TAK}, PTK2B (protein tyrosine kinase 2 beta) [NCBI Gene 2185] {aka CADTK, CAKB, FADK2, FAK2, PKB, PTK}, PIK3CD (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta) [NCBI Gene 5293] {aka APDS, IMD14, IMD14A, IMD14B, P110DELTA, PI3K}, RHO (rhodopsin) [NCBI Gene 6010] {aka CSNBAD1, OPN2, RP4}, PRRT2 (proline rich transmembrane protein 2) [NCBI Gene 112476] {aka BFIC2, BFIS2, DSPB3, DYT10, EKD1, FICCA}, AKT1 (AKT serine/threonine kinase 1) [NCBI Gene 207] {aka AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA}, YAP1 (Yes1 associated transcriptional regulator) [NCBI Gene 10413] {aka COB1, YAP, YAP-1, YAP2, YAP65, YKI}
- **Diseases:** constipation (MESH:D003248), inflammation (MESH:D007249), digestive disturbances (MESH:D004828), enteric neuropathies (MESH:D007418), megacolon (MESH:D008531), neuropathies (MESH:D009422), SCI (MESH:D013119), HSCR (MESH:D006627), insomnia (MESH:D007319)
- **Chemicals:** LY294002 (MESH:C085911), IRVJ (-), iridoid (MESH:D039823)
- **Species:** Rattus norvegicus (brown rat, species) [taxon 10116], Homo sapiens (human, species) [taxon 9606], Valeriana jatamansi (species) [taxon 59170]
- **Cell lines:** PC12 — Rattus norvegicus (Rat), Rat adrenal gland pheochromocytoma, Cancer cell line (CVCL_0481)

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Source: https://tomesphere.com/paper/PMC11832513