# Radiologic Assessment of Acute Aortic Syndrome With Multiple Penetrating Atheromatous Ulcers: A Case Report

**Authors:** Harminder Sandhu, Derrick L Barr, Lauri Tyre

PMC · DOI: 10.7759/cureus.77633 · Cureus · 2025-01-18

## TL;DR

This case report describes a rare instance of multiple aortic wall ulcers discovered in an elderly patient, highlighting the importance of early detection to prevent life-threatening complications.

## Contribution

The novelty lies in the rare presentation of multiple penetrating atheromatous ulcers combined with a ductus diverticulum, emphasizing diagnostic challenges and management strategies.

## Key findings

- Multiple penetrating atheromatous ulcers were incidentally discovered in the aortic arch and descending thoracic aorta.
- A ductus diverticulum was identified alongside the ulcers, adding complexity to the case.
- The patient was managed with high-dose statin therapy and scheduled follow-up imaging.

## Abstract

Acute aortic syndromes (AAS) include life-threatening conditions like penetrating atheromatous ulcer (PAU), which occurs when an atherosclerotic plaque erodes through the aortic wall. This can lead to complications such as intramural hematoma, pseudoaneurysm, or aortic rupture, especially in the ascending aorta. PAUs typically affect older males with atherosclerosis and are most commonly found in the lower descending thoracic aorta, with multiple PAUs being rare. This report highlights a case involving the incidental discovery of multiple PAUs and an associated ductus diverticulum, and it discusses their presentation and management. An 88-year-old male with a history of hypertension, diabetes, and pulmonary fibrosis presented with right-sided upper quadrant and chest pain radiating to the back. Initial imaging suggested progression of pulmonary fibrosis or an infection, but a subsequent CT angiogram revealed at least 12 focal outpouchings in the distal aortic arch and proximal descending thoracic aorta, compatible with PAUs. Additionally, a ductus diverticulum was identified. The patient was managed with high-dose statin therapy and scheduled for follow-up CTA in three months. This case highlights the incidental discovery of multiple PAUs and a ductus diverticulum, underscoring the rarity and complexity of PAU presentations. It emphasizes the importance of including PAU in the differential diagnosis for patients presenting with chest pain, especially when symptoms are atypical or overlap with other conditions. Early identification and management are crucial to prevent severe complications such as aortic dissection or rupture.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015), pulmonary fibrosis (MONDO:0002771)

## Full-text entities

- **Diseases:** aortic rupture (MESH:D001019), pseudoaneurysm (MESH:D017541), atherosclerosis (MESH:D050197), diabetes (MESH:D003920), chest pain (MESH:D002637), aortic dissection (MESH:D000784), hematoma (MESH:D006406), infection (MESH:D007239), ductus diverticulum (MESH:D004240), rupture (MESH:D012421), AAS (MESH:D000208), Aortic Syndrome (MESH:D000094683), hypertension (MESH:D006973), pulmonary fibrosis (MESH:D011658), Atheromatous Ulcers (MESH:D058226), PAU (MESH:D000094667)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11832285/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11832285/full.md

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Source: https://tomesphere.com/paper/PMC11832285