# Extensive Atrial Fibrosis and Recalcitrant Atrial Fibrillation: A Case Report and Brief Literature Review

**Authors:** Edinen Asuka, Olugbenga Arole, Andrew Ndakotsu

PMC · DOI: 10.7759/cureus.79169 · Cureus · 2025-02-17

## TL;DR

This paper presents a case of a 57-year-old man with severe atrial fibrosis and persistent atrial fibrillation, exploring the connection between the two conditions and treatment challenges.

## Contribution

The paper highlights the role of extensive atrial fibrosis in recalcitrant atrial fibrillation and reviews current literature and imaging approaches.

## Key findings

- Extensive atrial fibrosis is a significant factor in the recurrence of atrial fibrillation.
- Imaging modalities are crucial for diagnosing and managing cases of atrial fibrosis and atrial fibrillation.
- Treatment options vary and face challenges due to the complexity of the underlying pathophysiology.

## Abstract

Atrial fibrillation is one of the most common supraventricular arrhythmias. It has multiple etiologies, some of which include advanced age, hypertension, valvular heart disease, hyperthyroidism, sleep apnea, ischemic heart disease, cardiomyopathy, and certain medications. Herein, we will discuss a case of extensive atrial fibrosis in a 57-year-old male with recalcitrant atrial fibrillation, the significant role extensive atrial fibrosis plays in the recurrence of atrial fibrillation, a brief pathophysiologic interplay between both pathologies based on current literature and research, and various imaging modalities and treatment options utilized in these cases. Likewise, we will also outline some challenges faced or worth keeping in mind when using the various imaging modalities pertaining to the above subject matter.

## Linked entities

- **Diseases:** atrial fibrillation (MONDO:0004981), hyperthyroidism (MONDO:0004425), sleep apnea (MONDO:0005296), ischemic heart disease (MONDO:0024644), cardiomyopathy (MONDO:0004994)

## Full-text entities

- **Diseases:** hypertension (MESH:D006973), Atrial Fibrillation (MESH:D001281), sleep apnea (MESH:D012891), Atrial Fibrosis (MESH:D005355), hyperthyroidism (MESH:D006980), cardiomyopathy (MESH:D009202), ischemic heart disease (MESH:D017202), supraventricular arrhythmias (MESH:D001145), valvular heart disease (MESH:D006349)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11832057/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC11832057/full.md

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Source: https://tomesphere.com/paper/PMC11832057