Correction: Hao et al. Phosphorylation of Akt by SC79 Prevents Iron Accumulation and Ameliorates Early Brain Injury in a Model of Experimental Subarachnoid Hemorrhage. Molecules 2016, 21, 325

Abstract

Figures

SC79 administration after SAH largely rescues the impairment of Fe-S cluster biogenesis and alleviates the damage of neurons. (A) Western blot analysis for frataxin and ISCU. Upper panel: representative protein levels of frataxin and ISCU. Lower panel: quantitative data of the protein levels; (B) in-gel assay of aconitase activity. Upper panel: representative result. Lower panel: quantitative data of enzymatic activities; (C) enzymatic activity (upper panel) and Western blot (bottom panel) assays of XOD and CS; (D) representative slides of Nissl staining (left panel) and quantitative data (right panel) visualizing the neuronal cell outline and structure; and (E) alterations in brain water content. Data are expressed as mean ± SD (n = 8 in each group). * p < 0.05, * p < 0.001 vs. sham group, # p < 0.05, ### p < 0.001 vs. SAH group. ISCU, Fe-S cluster scaffold protein; XOD, xanthine oxidase; CS, citrate synthase.

Full text

Author Name Correction

In the published publication [1], there was an error regarding the author name. We changed Jiang Yu to Yu Jiang.

Error in Figure

In the original publication [1], there was a mistake in Figure 3D as published. There were overlapping panels in Figure 3D’s SAH and SAH+vehicle panels. The corrected Figure 3 appears below.

SC79 administration after SAH largely rescues the impairment of Fe-S cluster biogenesis and alleviates the damage of neurons. (A) Western blot analysis for frataxin and ISCU. Upper panel: representative protein levels of frataxin and ISCU. Lower panel: quantitative data of the protein levels; (B) in-gel assay of aconitase activity. Upper panel: representative result. Lower panel: quantitative data of enzymatic activities; (C) enzymatic activity (upper panel) and Western blot (bottom panel) assays of XOD and CS; (D) representative slides of Nissl staining (left panel) and quantitative data (right panel) visualizing the neuronal cell outline and structure; and (E) alterations in brain water content. Data are expressed as mean ± SD (n = 8 in each group). * p < 0.05, *** p < 0.001 vs. sham group, # p < 0.05, ### p < 0.001 vs. SAH group. ISCU, Fe-S cluster scaffold protein; XOD, xanthine oxidase; CS, citrate synthase.

The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.