# Using a mobile application for antiretroviral therapy adherence in people living with HIV: A longitudinal pilot study

**Authors:** Rejane Caetani, Susana L. Wiechmann, Jacques D. Brancher, Vitor H.F. Oliveira, Rafael Deminice

PMC · DOI: 10.4102/sajhivmed.v26i1.1646 · Southern African Journal of HIV Medicine · 2025-01-31

## TL;DR

A mobile app was tested to help people with HIV take their medication regularly, but it didn't significantly improve adherence despite being acceptable to users.

## Contribution

A pilot study evaluating a mobile app's feasibility and acceptability for improving ART adherence in people living with HIV.

## Key findings

- No significant improvement in ART adherence was observed in the mobile app group compared to the control group.
- The mobile app was considered acceptable by participants but showed low viability in improving adherence over time.
- A significant difference in adherence was found between groups, but not in time or interaction effects.

## Abstract

The success of HIV treatment hinges on consistent adherence to antiretroviral therapy (ART).

To conduct a longitudinal pilot study to assess the feasibility, acceptability and effectiveness of a mobile app to improve ART adherence.

This study included adults living with HIV and using ART, who were allocated into two groups according to their willingness to use the app: users of the mobile application for ART management (Mobile) and non-users (Control). The application was developed by the researchers, and uses an alarm system to record ART use. Adherence was also assessed using the ‘Cuestionario para la Evaluación de la Adhesión al Tratamiento Antiretroviral’ (CEAT-VIH) and the Multi-Method Tool questionnaire. Another questionnaire was administered to application users to assess acceptability. After 90 days, all the questionnaires were reapplied.

A significant difference in adherence was observed between the Mobile and Control groups (P = 0.04), but there was no significant difference in time (P = 0.2) or interaction (P = 0.5).

The application was not effective in improving ART adherence and showed low viability, but was considered acceptable among the participants.

## Full-text entities

- **Diseases:** HIV (MESH:D015658)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11830866/full.md

## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC11830866/full.md

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Source: https://tomesphere.com/paper/PMC11830866