# Posterior fossa astroblastoma: a case report of an extremely rare tumor with challenging diagnosis in a child and a review of literature

**Authors:** Ehab Shabo, Saida Zoubaa, Gerrit H. Gielen, Ralf Clauberg, Christian Wispel, Torsten Pietsch, Hartmut Vatter, Sevgi Sarikaya-Seiwert

PMC · DOI: 10.1007/s00381-025-06768-7 · Child's Nervous System · 2025-02-14

## TL;DR

A 7-year-old boy was diagnosed with a rare brain tumor called astroblastoma after experiencing nausea and vomiting, and the tumor was successfully removed.

## Contribution

This case highlights the diagnostic challenges and successful management of a rare posterior fossa astroblastoma in a child.

## Key findings

- The tumor was completely resected, leading to the patient's full recovery.
- Astroblastoma should be considered in the differential diagnosis for similar pediatric brain tumors.
- MRI features included a heterogeneous lesion with diffusion restriction and cystic components.

## Abstract

A 7-year-old boy presented to the hospital with recurrent nausea and vomiting over 2 weeks. A cranial MRI revealed a large heterogeneous lesion in the posterior fossa extending from the fourth ventricle to the foramen magnum with contact to the brainstem. The lesion showed moderate diffusion restriction and multiple small cystic components. The child underwent gross total resection. The primary histological findings suggested proliferative active tumor without further definition. The extended histological examination 3 weeks later confirmed the diagnosis of astroblastoma. Due to complete resection and full recovery of the patient, watchful waiting with radiological follow-up was recommended. Astroblastoma is an extremely rare tumor especially in the posterior fossa. However, it should be considered as a differential diagnosis in every tumor presenting the discussed radiological and histological features, especially in young aged patients.

## Linked entities

- **Diseases:** astroblastoma (MONDO:0016707)

## Full-text entities

- **Diseases:** Astroblastoma (MESH:D018302), nausea and vomiting (MESH:D020250), tumor (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC11828785/full.md

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Source: https://tomesphere.com/paper/PMC11828785