# Multisite Head and Neck Pediatric Posttransplant Lymphoproliferative Disorder: A Case Report

**Authors:** Lily Gao, Austin Hoke, Jarrett Jackson, Laura Petrauskas, Emily F. Mason, Asha Sarma, Debra Friedman, David Bearl, Daniel Dulek, Christopher Wootten, Jason Park

PMC · DOI: 10.1002/ccr3.70200 · Clinical Case Reports · 2025-02-14

## TL;DR

This case report highlights a pediatric head and neck lymphoproliferative disorder that resembled an infection, emphasizing the need for early diagnosis through biopsy.

## Contribution

The report underscores the importance of considering PTLD in pediatric transplant patients with poor response to standard treatments.

## Key findings

- PTLD can present with symptoms similar to infections in the head and neck region.
- Delayed diagnosis may occur due to minimal response to antibiotics or corticosteroids.
- Timely biopsy is crucial for confirming PTLD and initiating appropriate treatment.

## Abstract

Posttransplant lymphoproliferative disorder (PTLD) can mimic infectious processes in the head and neck. A high index of suspicion for PTLD must be maintained in pediatric transplant patients, and minimal response to antibiotics/corticosteroids should prompt timely biopsy of suspicious tissue to expedite the diagnosis and treatment of PTLD.

## Linked entities

- **Chemicals:** antibiotics (PubChem CID 46874763)
- **Diseases:** Posttransplant lymphoproliferative disorder (MONDO:0019088), infection (MONDO:0005550)

## Full-text entities

- **Diseases:** Head and Neck (MESH:D006258), PTLD (MESH:D008232)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11828662/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11828662/full.md

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Source: https://tomesphere.com/paper/PMC11828662