# A Rare Case of Atherosclerosis of the Angular Artery Manifested as a Nodular Lesion on the Skin and Review of the Literature

**Authors:** Wender Rodrigues Nazário, Marcondes Pedro Souza Novais, Anaíra Ribeiro Guedes Fonseca Costa, Débora de Oliveira Santos, Douglas Magallhães de Paula, Sérgio Vitorino Cardoso, Paulo Rogério de Faria

PMC · DOI: 10.1155/crid/6001887 · Case Reports in Dentistry · 2025-02-07

## TL;DR

This paper reports a rare case of atherosclerosis in the angular artery of an elderly man, presenting as a skin lesion, and emphasizes the importance of recognizing this condition in clinical practice.

## Contribution

The study presents the sixth documented case of atherosclerosis in the angular artery and highlights its clinical implications for dental clinicians.

## Key findings

- A painless nodular lesion at the labial commissure was diagnosed as atherosclerosis of the angular artery.
- No recurrence or arterial issues were observed after 6 months of follow-up.
- Dental clinicians should consider this rare condition in elderly patients with chronic systemic diseases.

## Abstract

Atherosclerosis is an age-related disease affecting the tunica intima of large and medium-sized arteries. Its occurrence in extracranial head and neck arteries is rare, with only five cases reported. This study is aimed at reporting the sixth case of atherosclerosis of the angular artery, a branch of the facial artery, in an elderly male patient with a history of hypertension. Morphological characterization using special stains and a literature review are included. Clinically, a painless, nodular lesion measuring 1.2 cm was observed at the right labial commissure. The lesion was excised, and atherosclerosis of the angular artery was diagnosed. After 6 months, there was no recurrence or other arterial issues. Despite its rarity in the oral and maxillofacial region, dental clinicians must be aware of this condition and its clinical manifestations, especially in elderly patients with chronic systemic diseases, to establish an accurate diagnosis.

## Linked entities

- **Diseases:** atherosclerosis (MONDO:0005311)

## Full-text entities

- **Diseases:** hypertension (MESH:D006973), Nodular Lesion on (MESH:D020518), systemic diseases (MESH:D034721), Atherosclerosis (MESH:D050197), artery (MESH:D012078)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11828654/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC11828654/full.md

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Source: https://tomesphere.com/paper/PMC11828654