# Hidradenitis Suppurativa and Recurrent Peripheral Ulcerative Keratitis: A Case Report

**Authors:** Klara Ambaye, Victor Cox, Abhishek Naidu, Aruoriwo Oboh-Weilke

PMC · DOI: 10.7759/cureus.77494 · Cureus · 2025-01-15

## TL;DR

A patient with hidradenitis suppurativa experienced a flare-up along with a rare eye condition called peripheral ulcerative keratitis, which improved with steroid treatment.

## Contribution

This case report adds to the evidence linking hidradenitis suppurativa with peripheral ulcerative keratitis as a rare ocular complication.

## Key findings

- The patient's symptoms resolved with a combination of topical and oral steroids.
- The case supports the hypothesis that hidradenitis suppurativa may underlie the development of peripheral ulcerative keratitis.
- The association between hidradenitis suppurativa and peripheral ulcerative keratitis is less frequently reported compared to other ocular manifestations.

## Abstract

This case report highlights a rare presentation of a hidradenitis suppurativa (HS) flare occurring concurrently with peripheral ulcerative keratitis (PUK) in a patient with a longstanding history of HS. HS is a chronic inflammatory skin condition known to be associated with various ocular manifestations, including inflammatory eye diseases (IEDs) such as anterior uveitis. Although the link between HS and IED is well documented, the association between HS and PUK is less frequently reported. Previous cases have demonstrated improvement in keratitis among HS patients using treatments ranging from topical steroids to systemic immunosuppressive therapies. In this case, the patient’s symptoms resolved with a combination of topical and oral steroids, supporting the hypothesis that HS may underlie the development of PUK in such cases. This report adds to the growing body of evidence connecting HS with ocular complications and underscores PUK as a rare but significant manifestation of the disease.

## Linked entities

- **Diseases:** hidradenitis suppurativa (MONDO:0006559), anterior uveitis (MONDO:0006651)

## Full-text entities

- **Diseases:** inflammatory (MESH:D007249), IEDs (MESH:D005128), anterior uveitis (MESH:D014606), HS (MESH:D017497), PUK (MESH:D003320), skin condition (MESH:D012871), keratitis (MESH:D007634)
- **Chemicals:** steroids (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11828476/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11828476/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC11828476/full.md

---
Source: https://tomesphere.com/paper/PMC11828476