# Dilated Cardiomyopathy and Hyperthyroidism: A Case Report and Literature Review

**Authors:** Oussama Elgharnati, Ikram Damoune, Abdelmajid Chraibi

PMC · DOI: 10.7759/cureus.77481 · Cureus · 2025-01-15

## TL;DR

A 45-year-old patient with hyperthyroidism developed reversible dilated cardiomyopathy, which improved with timely treatment.

## Contribution

This case report adds to the understanding of hyperthyroidism-induced DCM and emphasizes early diagnosis and treatment.

## Key findings

- Hyperthyroidism-induced DCM was reversed with carbimazole and propranolol within three months.
- Early diagnosis and treatment are crucial to prevent irreversible heart damage.
- Multidisciplinary collaboration is needed for effective management of such cases.

## Abstract

Dilated cardiomyopathy (DCM) is a rare but potentially reversible complication of hyperthyroidism, often resulting from severe thyrotoxicosis, leading to ventricular dilatation and reduced systolic function. A 45-year-old patient presented with progressive dyspnea and peripheral edema. Laboratory tests and imaging confirmed hyperthyroidism-induced DCM with a reduced ejection fraction (30%). Treatment with carbimazole and propranolol resulted in the normalization of thyroid function and cardiac recovery within three months. Hyperthyroidism can induce cardiac remodeling through genomic and non-genomic mechanisms of thyroid hormones, leading to reversible DCM. Early diagnosis and management are essential to avoid long-term complications, as delayed treatment may result in irreversible myocardial damage. This case highlights the need for multidisciplinary collaboration.

## Linked entities

- **Chemicals:** carbimazole (PubChem CID 31072), propranolol (PubChem CID 4946)
- **Diseases:** dilated cardiomyopathy (MONDO:0005021), hyperthyroidism (MONDO:0004425)

## Full-text entities

- **Diseases:** DCM (MESH:D002311), thyrotoxicosis (MESH:C566386), ventricular dilatation (MESH:C566255), peripheral edema (MESH:D004487), cardiac remodeling (MESH:D020257), Hyperthyroidism (MESH:D006980), myocardial damage (MESH:D009202), dyspnea (MESH:D004417)
- **Chemicals:** propranolol (MESH:D011433), carbimazole (MESH:D002231)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11827712/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11827712/full.md

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Source: https://tomesphere.com/paper/PMC11827712