# A Case Report of Crohn’s Disease with Atypical Manifestations

**Authors:** Maedeh Esmailzadeh, Masoumeh Safaee

PMC · DOI: 10.31661/gmj.v13i.3540 · Galen Medical Journal · 2024-10-15

## TL;DR

This case report describes a 31-year-old man with Crohn’s disease that presented with unusual symptoms, leading to a delayed diagnosis and surgery.

## Contribution

The paper highlights the diagnostic challenges of atypical Crohn’s disease presentations and the value of a multidisciplinary approach.

## Key findings

- The patient presented with drug-resistant abdominal pain and a distended abdomen, initially suspected as malignancy.
- Surgery revealed necrotic masses in the cecum and sigmoid, later confirmed as Crohn’s disease with no systemic inflammation.
- The patient recovered well post-surgery and was referred for ongoing gastroenterology care.

## Abstract

Background: Crohn’s disease, a chronic inflammatory bowel disease, is
characterized by inflammation of the gastrointestinal tract. While it typically
manifests with abdominal pain, diarrhea, and weight loss, atypical presentations
may arise, presenting diagnostic challenges. This case report aims to highlight
the diagnostic challenges posed by atypical manifestations of Crohn’s disease.
Case Presentation: A 31-year-old male sought medical attention in the Emergency
Department due to drug-resistant abdominal pain and a distended abdomen.
Following a thorough examination, including colonoscopy and surgical
consultation, malignancy was suspected, prompting total colectomy and
ileum-to-rectum anastomosis. Two large necrotic masses with purulent secretions
were discovered in the cecum and sigmoid during the surgical procedure.
Subsequent pathology results confirmed the diagnosis of Crohn’s disease, with no
evidence of inflammation in other organs. The patient experienced a smooth
recovery without surgical complications and was subsequently referred to a
gastroenterology specialist for further management. Conclusion: This case
emphasizes the importance of a multidisciplinary approach, including surgical
and gastroenterology expertise, in the management and effective treatment of
such cases in Crohn’s disease.

## Linked entities

- **Diseases:** Crohn’s disease (MONDO:0005011)

## Full-text entities

- **Diseases:** weight loss (MESH:D015431), necrotic (MESH:D009336), malignancy (MESH:D009369), inflammation of the gastrointestinal tract (MESH:D005770), inflammatory bowel disease (MESH:D015212), diarrhea (MESH:D003967), Crohn's Disease (MESH:D003424), abdominal pain (MESH:D015746), inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11826388/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11826388/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11826388/full.md

---
Source: https://tomesphere.com/paper/PMC11826388