# Oncocytic papillary renal cell carcinoma (OPRCC): 2 case report and literature review

## TL;DR

This paper presents two cases of a rare kidney cancer called OPRCC and reviews the literature to improve understanding and diagnosis of this condition.

## Contribution

The paper adds two new clinical cases and provides insights into the diagnosis and management of OPRCC.

## Key findings

- OPRCC is a rare and distinct subtype of papillary renal cell carcinoma.
- Diagnosis and post-operative management of OPRCC remain challenging due to uncertain morphology and genetic features.
- Subdividing OPRCC from PRCC improves diagnostic precision and patient management.

## Abstract

Oncocytic papillary renal cell carcinoma (OPRCC) is a new papillary renal cell carcinoma (OPRCC) added to the 2016 WHO Classification of Tumors of the Urinary and Male Reproductive System. It is a subtype of carcinoma, PRCC, which is very rare and it is very characteristic and interesting. The morphology, immunophenotype, genetic characteristics and prognosis of OPRCC are uncertain, so the diagnosis and post-operative management of OPRCC are challenging. Recently, two patients with OPRCC have been treated in our hospital, both of whom have undergone surgical treatment. The information of these two cases is described as follows, and the literature is further reviewed to share the current diagnosis and treatment characteristics of OPRCC and the research progress after surgery. At the same time, the diagnosis of OPRCC disease is subdivided from PRCC disease, and the diagnosis of OPRCC disease is more precise. To optimize the individualized management of patients with renal cell carcinoma in order to improve the understanding and diagnosis of the disease.