# A Case of Nocardia kroppenstedtii Infection Successfully Treated With a Multidisciplinary Approach

**Authors:** Francesco Foglia, Annalisa Ambrosino, Giuseppe Greco, Annalisa Chianese, Carla Zannella, Francesca Cinone, Alfonso Reginelli, Diego Sandro Giordano, Giovanni Tortorella, Maria Teresa Laieta, Anna De Filippis, Massimiliano Galdiero, Rita Greco, Emiliana Finamore

PMC · DOI: 10.1155/crdi/6452173 · Case Reports in Infectious Diseases · 2025-02-06

## TL;DR

A rare Nocardia infection in an older patient was successfully treated using a multidisciplinary medical approach.

## Contribution

This paper reports a rare clinical case of Nocardia kroppenstedtii infection in an immunocompetent individual.

## Key findings

- Nocardia kroppenstedtii was isolated from a 69-year-old patient's subxiphoid and leg formations.
- The infection was successfully managed through antimicrobial stewardship and multidisciplinary care.
- Only five clinically relevant cases of this rare species have been documented in literature.

## Abstract

Nocardia species constitute a diverse group of microorganisms classified as aerobic actinomyces. Among these species, many have been implicated as causative agents of severe human infections, particularly in immunocompromised patients, affecting lungs, skin, and nervous system. Here, we described a rare species, identified as Nocardia kroppenstedtii, isolated at the Complex Operative Unit of Virology and Microbiology from the subxiphoid formation and pseudonodular formation in the left leg of a 69-year-old immunocompetent patient, who was hospitalized and treated at the Complex Operative Unit of Internal Medicine and Geriatrics of the University Hospital of Campania “Luigi Vanvitelli” in an antimicrobial diagnostic stewardship context. This rare pathogen was first isolated in 2014 from a bronchoalveolar lavage sample obtained from a lung transplant recipient. Since then, only five cases of clinical interest have been described in literature.

## Linked entities

- **Species:** Nocardia kroppenstedtii (taxon 341199)

## Full-text entities

- **Diseases:** infections (MESH:D007239)
- **Species:** Homo sapiens (human, species) [taxon 9606], Nocardia kroppenstedtii (species) [taxon 341199], Actinomyces (genus) [taxon 1654]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11825202/full.md

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Source: https://tomesphere.com/paper/PMC11825202