# Thyroid Storm Triggered by Rotavirus Infection in a 10-Year-Old Girl

## TL;DR

A 10-year-old girl with Graves' disease developed thyroid storm triggered by rotavirus infection, suggesting a possible link between gastrointestinal infections and thyroid storm.

## Contribution

This case report highlights a novel association between rotavirus infection and thyroid storm in a pediatric patient with Graves' disease.

## Key findings

- Rotavirus infection can trigger thyroid storm in patients with Graves' disease.
- Symptoms of rotavirus can mimic those of thyroid storm, complicating diagnosis.
- The case suggests the need to investigate potential pathogens in thyroid storm cases.

## Abstract

We encountered a case of Graves' disease in a pediatric patient who presented with thyroid storm (TS), the onset of which was triggered by rotavirus infection. Rotavirus is commonly associated with severe watery diarrhea, vomiting, fever, and dehydration—particularly in infants and young children. In more severe cases, it can also lead to altered consciousness and seizures. These symptoms can resemble those of TS, even in the absence of pre-existing hyperthyroidism. In cases of hyperthyroidism, these symptoms confirm the criteria for TS. Therefore, it is possible that some cases of TS are triggered and caused by gastrointestinal conditions such as rotavirus infection. Our case highlights the need for further investigation into the potential triggering pathogens in patients with TS to better clarify details regarding the patient's status or disease pathogenesis.