# Case report: Scleromalacia caused by rheumatoid arthritis combined with high intraocular pressure, first discovered due to ocular trauma

**Authors:** Yanyan Zhang, Yanyan Wang, Ruihao Xu, Tianyu Wang, Yuhao Zhang, Jinghai Mao, Quanyong Yi

PMC · DOI: 10.3389/fmed.2024.1504807 · Frontiers in Medicine · 2025-01-30

## TL;DR

A man with rheumatoid arthritis developed rare eye condition scleromalacia after trauma, highlighting the need for attention to autoimmune disease effects on eye health.

## Contribution

This case report highlights a rare combination of scleromalacia and high intraocular pressure in a rheumatoid arthritis patient.

## Key findings

- Scleromalacia was diagnosed after ocular trauma revealed extremely thin and bluish sclera.
- Emergency surgery showed scleral thinning to 1/5 to 1/3 of normal thickness.
- The case emphasizes the ocular risks of systemic autoimmune diseases like rheumatoid arthritis.

## Abstract

A 53-year-old man with rheumatoid arthritis was first diagnosed with scleromalacia at the ophthalmology clinic after experiencing ocular trauma. The patient presented with decreased vision and abnormalities were subsequently found in his other eye. An ophthalmologist performed emergency debridement and suturing surgery on the ruptured right eyeball, discovering that the sclera was thinned to only 1/5 to 1/3 of its normal thickness. After the operation, the ophthalmologist examined the patient’s right eye and noted similar bluish scleral changes along with elevated intraocular pressure. In this case, we report a relatively rare instance of scleromalacia combined with ocular hypertension, which was definitively diagnosed following emergency ophthalmic surgery. The patient exhibited extremely thin and bluish sclera in both eyes. This case once again underscores the importance of clinicians paying close attention to the impact of systemic autoimmune diseases on ocular health.

## Linked entities

- **Diseases:** rheumatoid arthritis (MONDO:0008383)

## Full-text entities

- **Diseases:** ocular hypertension (MESH:D009798), systemic autoimmune diseases (MESH:D020274), decreased vision (MESH:D014786), intraocular pressure (MESH:D064090), ocular trauma (MESH:D014947), rheumatoid arthritis (MESH:D001172)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11823624/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11823624/full.md

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Source: https://tomesphere.com/paper/PMC11823624