# A comprehensive multidisciplinary approach for identifying asbestos exposure among underground workers

**Authors:** Alejandro Salvado, Lilian Capone, Paula Zamorano, Mayra Samudio, María Teresa Garcia-de-Dávila, Glenda Ernst

PMC · DOI: 10.47626/1679-4435-2024-1271 · Revista Brasileira de Medicina do Trabalho · 2025-01-31

## TL;DR

This study identifies asbestos-related diseases in underground workers, showing that long-term exposure increases risk.

## Contribution

The study provides new insights into the prevalence and risk factors of asbestos-related diseases in a specific occupational group.

## Key findings

- 2.8% of participants had asbestos-related diseases, with 0.22% diagnosed with lung cancer.
- Occupational exposure exceeding 20 years significantly increased the risk of asbestos-related diseases.
- Findings align with other surveillance programs on asbestos-exposed workers.

## Abstract

Inhalation of asbestos fibers can lead to a range of diseases, including
asbestosis, pleural plaques, lung cancer, and malignant mesothelioma.
Despite regulatory efforts, asbestos-related diseases remain a significant
public health issue.

This study aimed to assess the characteristics and prevalence of
asbestos-related diseases among exposed workers.

We conducted a descriptive cohort study with underground workers in Buenos
Aires, Argentina, from March 2018 to March 2023. A comprehensive screening
and surveillance program, including medical examinations, was implemented to
identify exposure-related signs and symptoms. Histological sections from
paraffin-embedded tissue blocks were analyzed using light and polarization
microscopy for lung cancer cases.

A total of 2,690 participants were included, of whom 2.8% (n = 77) had
asbestos-related diseases and 0.22% (n = 6) had lung cancer. Occupational
exposure exceeding 20 years was significantly associated with an elevated
risk of asbestos-related diseases (odd ratio: 3.02; 95%CI 1.7-5.3).

The prevalence of occupational diseases among underground workers was
consistent with findings from other surveillance programs for
asbestos-exposed workers. Occupational exposure exceeding 20 years emerged
as a significant risk factor, markedly increasing the likelihood of
asbestos-related diseases

## Linked entities

- **Diseases:** asbestosis (MONDO:0016466), lung cancer (MONDO:0005138), malignant mesothelioma (MONDO:0006292)

## Full-text entities

- **Diseases:** malignant mesothelioma (MESH:D000086002), asbestos-related diseases (MESH:D001195), occupational diseases (MESH:D009784), pleural plaques (MESH:D010995), lung cancer (MESH:D008175)
- **Chemicals:** paraffin (MESH:D010232), asbestos (MESH:D001194), asbestos-related diseases (-)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11822978/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11822978/full.md

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Source: https://tomesphere.com/paper/PMC11822978