# Featured Cover

**Authors:** Richie P. Goulding, Braeden T. Charlton, Ellen A. Breedveld, Matthijs van der Laan, Anne R. Strating, Wendy Noort, Aryna Kolodyazhna, Brent Appelman, Michèle van Vugt, Anita E. Grootemaat, Nicole N. van der Wel, Jos J. de Koning, Frank W. Bloemers, Rob C. I. Wüst

PMC · DOI: 10.1111/acel.70017 · Aging Cell · 2025-02-13

## TL;DR

This study shows that mitochondrial fragmentation in skeletal muscle is linked to a decline in physical ability with age.

## Contribution

The novel contribution is identifying mitochondrial fragmentation as a predictor of age-related physical decline.

## Key findings

- Mitochondrial fragmentation in skeletal muscle is associated with reduced physical capacity in aging.
- The study provides a potential biomarker for age-related physical decline.
- Findings suggest a link between mitochondrial dynamics and aging-related health outcomes.

## Abstract

Cover legend: The cover image is based on the article Skeletal muscle mitochondrial fragmentation predicts age‐associated decline in physical capacity by Rob Wüst et al., https://doi.org/10.1111/acel.14386.

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11822646/full.md

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Source: https://tomesphere.com/paper/PMC11822646