# Impact of a cerebrospinal fluid diagnostic stewardship intervention on quantity of tests, length of stay, antibiotic prescriptions, and cost

**Authors:** Aaron Pathak, Sabra Shay, Todd Lasco, Mayar Al Mohajer

PMC · DOI: 10.1017/ash.2025.17 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2025-02-11

## TL;DR

A diagnostic stewardship program for cerebrospinal fluid testing in suspected meningitis did not change costs or outcomes.

## Contribution

A new diagnostic stewardship approach was implemented to reduce unnecessary cerebrospinal fluid tests.

## Key findings

- The intervention limited cerebrospinal fluid tests to seven common assays.
- There was no significant change in testing costs or clinical outcomes.
- Antibiotic prescriptions and length of stay were unaffected by the intervention.

## Abstract

Redundant and low-value cerebrospinal fluid analysis for suspected meningitis can increase costs and antimicrobial use. Our diagnostic stewardship intervention limited available infectious disease cerebrospinal fluid assays to seven common tests, including a multiplex polymerase chain reaction panel. There was no significant difference in the cost of testing or clinical outcomes.

## Linked entities

- **Diseases:** meningitis (MONDO:0021108)

## Full-text entities

- **Diseases:** meningitis (MESH:D008580), infectious disease (MESH:D003141)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11822616/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11822616/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11822616/full.md

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Source: https://tomesphere.com/paper/PMC11822616