# Circumcision‐Associated Penile Papules: A Novel Complication With Unclear Etiology

**Authors:** Mingshuang Zhang, Rongqing Yang, Jie Huang

PMC · DOI: 10.1111/jocd.70034 · Journal of Cosmetic Dermatology · 2025-02-12

## TL;DR

This paper reports a new complication of circumcision: penile papules that appear months to years later and can be mistaken for genital warts.

## Contribution

The paper introduces a previously unreported complication of circumcision with unclear causes and cosmetic concerns.

## Key findings

- Six adult males developed penile papules months to years after circumcision.
- The papules were larger, unevenly distributed, and not arranged like typical pearly penile papules.
- The condition poses a cosmetic issue and risk of misdiagnosis as genital warts.

## Abstract

To report six patients with penile papules after circumcision to attract the attention of clinicians and patients to the complication associated with circumcision.

We reported several clinical cases presenting with these papules following circumcision. Cases were reassessed for clinical characteristics, histopathological features, and potential risk factors.

A series of six adult male cases were identified, with papules appearing asymptomatically months to years after circumcision. The papules were larger, exhibited uneven distribution, and lacked the typical arrangement of pearly penile papules, posing a cosmetic concern and a risk of misdiagnosis as genital warts.

This study presents a previously unreported complication of circumcision with significant implications for patient care. Further investigation is warranted to understand the etiology and develop strategies for prevention and management.

## Full-text entities

- **Diseases:** genital warts (MESH:D003218), Penile Papules (MESH:D010409), papules (MESH:D000169)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11822241/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC11822241/full.md

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Source: https://tomesphere.com/paper/PMC11822241