A novel framework for modeling quarantinable disease transmission
Wenchen Liu, Chang Liu, Dehui Wang, Yiyuan She
TL;DR
This paper introduces a new model for tracking disease spread that better accounts for real-world complexities like asymptomatic transmission and delayed diagnosis.
Contribution
The CURNDS model introduces adaptive power laws and dynamic transmission rates to improve disease transmission modeling.
Findings
The model accurately estimates undetected infections and undocumented deaths from COVID-19 data.
CURNDS challenges the assumption of homogeneous mixing in traditional epidemiological models.
The framework offers new insights into the spread of different COVID-19 strains.
Abstract
The COVID-19 pandemic has significantly challenged traditional epidemiological models due to factors such as delayed diagnosis, asymptomatic transmission, isolation-induced contact changes, and underreported mortality. In response to these complexities, this paper introduces a novel CURNDS model prioritizing compartments and transmissions based on contact levels, rather than merely on symptomatic severity or hospitalization status. The framework surpasses conventional uniform mixing and static rate assumptions by incorporating adaptive power laws, dynamic transmission rates, and spline-based smoothing techniques. The CURNDS model provides accurate estimates of undetected infections and undocumented deaths from COVID-19 data, uncovering the pandemic’s true impact. Our analysis challenges the assumption of homogeneous mixing between infected and non-infected individuals in traditional…
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Taxonomy
TopicsCOVID-19 epidemiological studies · SARS-CoV-2 and COVID-19 Research · Mathematical and Theoretical Epidemiology and Ecology Models