# A Novel Medical Device for Airway Clearance

**Authors:** Nir Helper, Moshe Ashkenazi, Gil Sokol, Adi Dagan, Ori Efrati

PMC · DOI: 10.3390/jcm14030907 · 2025-01-30

## TL;DR

A new medical device called LibAirty was found to be more effective than existing methods for airway clearance in bronchiectasis patients.

## Contribution

LibAirty, a novel medical device for airway clearance, was tested and shown to outperform traditional methods like HFCWO.

## Key findings

- LibAirty produced significantly more sputum clearance than High-Frequency Chest Wall Oscillator (HFCWO).
- LibAirty's performance was comparable to that of a human respiratory physiotherapist.
- No adverse events were recorded during the study.

## Abstract

Background: Airway clearance techniques are a key element in the daily treatment of people with bronchiectasis. There are several methods and devices to assist in effective airway clearance. We investigated LibAirty, a novel medical device, and compared it with the common practice performed today. Methods: Twenty adults enrolled, and each one had three different treatments in a randomized order: a human respiratory physiotherapist, a High-Frequency Chest Wall Oscillator, and LibAirty with BiPAP. The outcome parameters were mucus weight and a questionnaire. Further studies were performed to investigate LibAirty with hypertonic saline (HS) inhalation and using the device as a standalone. Results: No adverse events were recorded. The sputum amount expectorated in all arms using LibAirty was 14.4 ± 11.1 g with BIPAP, 16.4 ± 7 g with HS, and 11.3 ± 4.1 g for the standalone treatment. For HFCWO, 4.45 ± 3.28 g was obtained, and for CPT, 15.9 ± 11.1 g was obtained. The amount obtained by LibAirty (all arms) was significantly higher than HFCWO. Conclusions: All arms of LibAirty were superior to HFCWO and similar to the human physiotherapist. Further studies should be performed to investigate the long-term effects of LibAirty.

## Linked entities

- **Diseases:** bronchiectasis (MONDO:0004822)

## Full-text entities

- **Diseases:** bronchiectasis (MESH:D001987)
- **Chemicals:** HFCWO (-), HS (MESH:D012965), CPT (MESH:C000708228)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11818876/full.md

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Source: https://tomesphere.com/paper/PMC11818876