# MitraClip Procedure in Advanced Heart Failure and Severe Mitral Regurgitation: Case Report and Literature Review

**Authors:** Camilla Cirelli, Anna Merlo, Alice Calabrese, Luca Fazzini, Luigi Fiocca, Michele Senni, Massimo Iacoviello, Mauro Gori

PMC · DOI: 10.3390/jcm14031011 · 2025-02-05

## TL;DR

This paper presents a successful case of using the MitraClip device to treat severe heart failure and mitral regurgitation, along with a literature review.

## Contribution

The paper contributes a case report of emergent MitraClip use in advanced heart failure, highlighting its potential in this challenging clinical scenario.

## Key findings

- The MitraClip intervention was successful in a patient with advanced heart failure and severe mitral regurgitation.
- The literature review supports the potential of MitraClip as a treatment option in chronic heart failure.
- Safety and efficacy of MitraClip in acute heart failure remain areas requiring further study.

## Abstract

Mitral regurgitation (MR) is a common valvular disorder often seen in a severely dilated left ventricle (LV) and reduced LV function. In chronic heart failure (HF), severe functional MR increases preload, wall tension, LV workload, and worsening prognosis. The MitraClip device offers a percutaneous treatment option in HF, although its safety and efficacy in advanced and acute HF remain a gray zone. We present a successful case of the emergent MitraClip intervention in a patient with advanced HF and review the relevant literature.

## Linked entities

- **Diseases:** heart failure (MONDO:0005252)

## Full-text entities

- **Diseases:** MR (MESH:D008944), valvular disorder (MESH:D000082862), LV (MESH:D020257), HF (MESH:D006333)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11818264/full.md

---
Source: https://tomesphere.com/paper/PMC11818264