# tagtango: an application to compare single-cell annotations

**Authors:** Bernat Bramon Mora, Helen Lindsay, Antonin Thiébaut, Kenneth D Stuart, Raphael Gottardo

PMC · DOI: 10.1093/bioinformatics/btaf012 · Bioinformatics · 2025-01-11

## TL;DR

tagtango is a user-friendly tool for comparing single-cell cluster annotations and exploring biological differences visually.

## Contribution

tagtango introduces a novel R package and web application for intuitive comparison of single-cell annotations.

## Key findings

- tagtango simplifies the exploration of differences and similarities among clustering and annotation methods.
- The tool provides interactive visualizations to dissect biological differences across groups.
- It is portable and works seamlessly across multiple operating systems.

## Abstract

In this article, we present tagtango, an innovative R package and web application designed for robust and intuitive comparison of single-cell clusters and annotations. It offers an interactive platform that simplifies the exploration of differences and similarities among different clustering and annotation methods. Leveraging single-cell data analysis and different visualizations, it allows researchers to dissect the underlying biological differences across groups. tagtango is a user-friendly application that is portable and works seamlessly across multiple operating systems.

tagtango is freely available at https://github.com/bernibra/tagtango as an R package as well as an online web service at https://tagtango.unil.ch.

## Full-text entities

- **Genes:** PTPRC (protein tyrosine phosphatase receptor type C) [NCBI Gene 5788] {aka B220, CD45, CD45R, GP180, IMD105, L-CA}, CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11814489/full.md

## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC11814489/full.md

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Source: https://tomesphere.com/paper/PMC11814489