# Editorial: Cell cycle modulators: regulating the basic unit of life for disease treatment and tissue regeneration

**Authors:** Roberta Giordo, Audra N. Iness, Udhaya Kumar

PMC · DOI: 10.3389/fphar.2025.1554529 · Frontiers in Pharmacology · 2025-01-29

## Full-text entities

- **Genes:** BRAF (B-Raf proto-oncogene, serine/threonine kinase) [NCBI Gene 673] {aka B-RAF1, B-raf, BRAF-1, BRAF1, NS7, RAFB1}, KEAP1 (kelch like ECH associated protein 1) [NCBI Gene 9817] {aka INrf2, KLHL19}, SIRT6 (sirtuin 6) [NCBI Gene 51548] {aka SIR2L6, hSIRT6}, TXK (TXK tyrosine kinase) [NCBI Gene 7294] {aka BTKL, PSCTK5, PTK4, RLK, TKL}, KRAS (KRAS proto-oncogene, GTPase) [NCBI Gene 3845] {aka 'C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A}, NFE2L2 (NFE2 like bZIP transcription factor 2) [NCBI Gene 4780] {aka IMDDHH, NRF2, Nrf-2}, NRAS (NRAS proto-oncogene, GTPase) [NCBI Gene 4893] {aka ALPS4, CMNS, N-ras, NCMS, NRAS1, NS6}
- **Diseases:** NSCLC (MESH:D002289), neurological disorders (MESH:D009461), tumorigenesis (MESH:D063646), cognitive and behavioral deficits (MESH:D003072), CRC (MESH:D015179), fibrosis (MESH:D005355), keloids (MESH:D007627), cancer (MESH:D009369), HCC (MESH:D006528), neurotoxicity (MESH:D020258), Fibrotic conditions (MESH:D020763), fibrotic diseases (MESH:D004194)
- **Chemicals:** dasatinib (MESH:D000069439), ROS (-), METH (MESH:D008694), imidazole (MESH:C029899), PEITC (MESH:C058305)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC11814217