# Complete genome sequence of Staphylococcus epidermidis B273 and its epidermicin NI01 biosynthesis plasmid

## TL;DR

This paper presents the full genome sequence of a Staphylococcus epidermidis strain and a plasmid involved in producing a potent antimicrobial peptide.

## Contribution

The study provides the complete genome sequence of S. epidermidis B273 and identifies the plasmid responsible for epidermicin NI01 biosynthesis.

## Key findings

- The genome of S. epidermidis B273 includes a plasmid with the epidermicin NI01 biosynthetic gene cluster.
- Epidermicin NI01 is a broad-spectrum type II antimicrobial peptide.

## Abstract

The human skin commensal Staphylococcus epidermidis produces diverse, therapeutically relevant bacteriocins. We report the complete whole-genome sequence of the nasal isolate S. epidermidis B273, which contains a plasmid with the biosynthetic gene cluster for epidermicin NI01, a broad-spectrum type II antimicrobial peptide.