# Complete genome sequence of a penicillin-resistant Fusobacterium necrophorum subsp. funduliforme isolate from a tonsillitis patient

**Authors:** Bibek G C, Anders Jensen, Chenggang Wu

PMC · DOI: 10.1128/mra.01233-24 · 2024-12-20

## TL;DR

This paper presents the full genome of a penicillin-resistant bacteria from a tonsillitis patient, offering clues about antibiotic resistance.

## Contribution

The study provides the first complete genome sequence of a penicillin-resistant F. necrophorum subsp. funduliforme isolate.

## Key findings

- The genome includes a 2,440,359 bp chromosome and a 9,887 bp plasmid.
- The sequence reveals genetic factors linked to penicillin resistance in F. necrophorum.

## Abstract

We report the complete genome sequence of a penicillin-resistant Fusobacterium necrophorum subsp. funduliforme isolate, AJ79, from a tonsillitis patient. The AJ79 genome consists of a chromosome (2,440,359 bp) and plasmid (9,887 bp), providing insights into the genetic basis of penicillin resistance in F. necrophorum and its implications for treating tonsillitis.

## Linked entities

- **Chemicals:** penicillin (PubChem CID 2349)
- **Diseases:** tonsillitis (MONDO:0001039)
- **Species:** Fusobacterium necrophorum subsp. funduliforme (taxon 143387)

## Full-text entities

- **Diseases:** penicillin (MESH:D008586), tonsillitis (MESH:D014069)
- **Chemicals:** penicillin (MESH:D010406)
- **Species:** Fusobacterium necrophorum subsp. funduliforme (subspecies) [taxon 143387], Fusobacterium necrophorum (species) [taxon 859], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11812309/full.md

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Source: https://tomesphere.com/paper/PMC11812309