# UK cancer vaccine advance – Recognising and realising opportunities

**Authors:** Charles Craddock, Philip Earwaker, Matthew Fittall, Elisa Fontana, Divya Ganesh, Marco Gerlinger, Qamar Ghafoor, Robert P Jones, Victoria Kunene, Lennard Lee, Rebecca Lee, Siow-Ming Lee, Mark Linch, Martin Little, Justin Liu, Hayley McKenzie, Russell Petty, David J Pinato, Thomas Powles, Andrew Protheroe, Tim Robinson, Paul J Ross, Kai Keen Shiu, James Spicer, Stefan Symeonides, Michael Tilby, Dale Vimalachandran, Jenny Y Wang, Andrew Wardley, Helen Winter, Philip Beer, Philip Beer

PMC · DOI: 10.1017/pcm.2024.5 · 2025-01-20

## TL;DR

This paper discusses the UK's potential to lead in developing cancer vaccines by leveraging recent vaccine successes and fostering collaboration.

## Contribution

The paper outlines a strategic approach for advancing cancer vaccine development in the UK through partnerships and proactive strategies.

## Key findings

- The UK is well-positioned to pioneer cancer vaccine trials due to its vaccine capabilities.
- Collaboration with pharmaceutical partners is emphasized to accelerate cancer vaccine technology.
- Personalised and fixed cancer vaccines are highlighted as key areas for development.

## Abstract

Vaccines have revolutionised the field of medicine, eradicating and controlling many diseases. Recent pandemic vaccine successes have highlighted the accelerated pace of vaccine development and deployment. Leveraging this momentum, attention has shifted to cancer vaccines and personalised cancer vaccines, aimed at targeting individual tumour-specific abnormalities. The UK, now regarded for its vaccine capabilities, is an ideal nation for pioneering cancer vaccine trials. This article convened experts to share insights and approaches to navigate the challenges of cancer vaccine development with personalised or precision cancer vaccines, as well as fixed vaccines. Emphasising partnership and proactive strategies, this article outlines the ambition to harness national and local system capabilities in the UK; to work in collaboration with potential pharmaceutic partners; and to seize the opportunity to deliver the pace for rapid advances in cancer vaccine technology.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** cancer (MESH:D009369)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11811843/full.md

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Source: https://tomesphere.com/paper/PMC11811843