# Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report

**Authors:** Yong Xiao, Liang Liu, Ran Wang, Dong Wang, Liangyuan Geng, Xinhua Hu, Yong Liu, Chunfa Qian, Yuanjie Zou

PMC · DOI: 10.3389/fonc.2024.1493982 · Frontiers in Oncology · 2025-01-27

## TL;DR

A teenage girl had a ruptured brain tumor that was successfully removed and did not return after one year.

## Contribution

This case report highlights a rare instance of spontaneous rupture of a mature teratoma in the lateral ventricle and suggests effective treatment through resection and monitoring.

## Key findings

- Radiological findings showed oily globules in the ventricles and subarachnoid space.
- Gross total resection of the tumor led to a confirmed diagnosis of mature teratoma.
- The patient remained asymptomatic and recurrence-free for one year post-surgery without additional treatment.

## Abstract

We present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-dependent hormonal changes, which increase glandular secretion, cyst content volume, and intra-cystic pressure. The patient underwent gross total resection of the tumor, and the subsequent pathological examination confirmed the diagnosis of mature teratoma. Postoperatively, she was managed with routine follow-up without adjuvant chemotherapy or radiotherapy. During the 1-year follow-up period, the patient remained asymptomatic with no evidence of tumor recurrence. Based on this case, we recommend that gross total resection followed by close monitoring, without adjunctive chemotherapy or radiotherapy, can be an effective treatment strategy for patients with similar presentations.

## Linked entities

- **Diseases:** teratoma (MONDO:0002601)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), rupture (MESH:D012421), lateral ventricle teratoma (MESH:D013724)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC11807994/full.md

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Source: https://tomesphere.com/paper/PMC11807994