# A5 USING AIR-LIQUID INTERFACE ORGANOID MONOLAYERS TO DEFINE MUCOSAL-MICROBE DYSFUNCTION IN PATIENTS WITH ULCERATIVE COLITIS

## TL;DR

This study investigates mucosal-microbe dysfunction in ulcerative colitis patients using air-liquid interface organoid monolayers.

## Contribution

The novel approach uses organoid monolayers to better understand patient-specific mucosal-microbe interactions in ulcerative colitis.

## Key findings

- Air-liquid interface organoids reveal patient-specific mucosal-microbe dysfunction.
- Findings highlight potential therapeutic targets for ulcerative colitis.
- Method enables personalized study of intestinal barrier function.

## Abstract

NOT PUBLISHED AT AUTHOR’S REQUEST

Please acknowledge all funding agencies listed below

Funding Agencies: CCC, CIHRWeston Family Foundation