# Choroidal Neovascularization in a Pediatric Patient With Optic Disc Pit

**Authors:** Marwa Mukhtar, Malik Mudasser Yasin, Mohib Naseer

PMC · DOI: 10.7759/cureus.77231 · Cureus · 2025-01-10

## TL;DR

A 13-year-old girl with a rare optic disc pit developed choroidal neovascularization, which improved after anti-VEGF treatment.

## Contribution

Reports a rare case of CNV in a pediatric patient with optic disc pit and successful treatment with anti-VEGF injections.

## Key findings

- CNV was diagnosed in a 13-year-old girl with optic disc pit.
- Anti-VEGF injections led to improvement in CNV and significant visual recovery.
- Pediatric CNV associated with optic disc pit is rare but treatable.

## Abstract

Optic disc pit is a congenital anomaly of the optic disc which is usually asymptomatic, but some patients can develop optic disc pit maculopathy at some stage of life.

Choroidal neovascularization (CNV) is an abnormal growth of blood vessels into the neurosensory retina from choroidal vessels. Although CNV is not commonly seen in the pediatric age group, there are certain optic nerve head anomalies, like optic disc pit, optic nerve drusen, optic nerve head cavity abnormalities, etc., which are associated with CNV in children.

Here, we present a 13-year-old girl who was diagnosed with CNV in association with optic disc pit. She was given intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections. CNV got improved after anti-VEGF injections, along with significant improvement in vision.

## Linked entities

- **Diseases:** choroidal neovascularization (MONDO:0810000)

## Full-text entities

- **Genes:** VEGFA (vascular endothelial growth factor A) [NCBI Gene 7422] {aka L-VEGF, MVCD1, VEGF, VPF}
- **Diseases:** Optic Disc Pit (MESH:D009901), optic nerve head anomalies (MESH:D006259), CNV (MESH:D020256), congenital anomaly of the optic disc (MESH:C566924), optic nerve drusen (MESH:D015594)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC11807407/full.md

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Source: https://tomesphere.com/paper/PMC11807407